One drink of alcohol and at least 1 million cells will die and more with be damage to the point of not being able to function; let’s investigate this further.
Alcohol causes primary malnutrition by displacing nutrients in the diet and secondary malnutrition via malabsorption and cellular injury through direct cytotoxicity.
Hepatotoxicity results from metabolic disturbances associated with the oxidation of ethanol via liver alcohol dehydrogenase (ADH) and the redox changes produced by the generated NADH (the reduced form of nicotinamide adenine dinucleotide), which in turn affects the metabolism of lipids, carbohydrates, proteins, and purines
Alcohol is also oxidized in liver microsomes by an ethanol-inducible cytochrome P450, which contributes to the alcoholic’s tolerance and his increased vulnerability to the toxicity of industrial solvents, anesthetics, commonly prescribed drugs, over-the-counter analgesics, chemical carcinogens, and retinoids.
Increased acetaldehyde generation, with formation of protein adducts, results in antibody production, enzyme inactivation, decreased DNA repair, impaired utilization of oxygen, glutathione depletion, free radical-mediated toxicity, and increased collagen synthesis.
Therapy may eventually improve with the use of super nutrients such as S-adenosyl-L-methionine, which replenishes glutathione, restores methylation, and attenuates liver injury, which prevents cirrhosis.
Is it time for a nutrition evaluation to begin the alcohol detoxification process?